Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 5/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18718202 | 0.96 | FPR2 (0.36) | GRIN1GRIN2BFASNFPR2NAAA | |
| SCHEMBL8940715 | 0.95 | FPR2 (0.34) | GRIN1GRIN2BFASNFPR2FFAR4 | |
| SCHEMBL12999926 | 0.94 | FASN (0.32) | GRIN1GRIN2BFASN | |
| SCHEMBL8940751 | 0.94 | S1PR1 (0.34) | GRIN1GRIN2BFASNFPR2S1PR1 | |
| SCHEMBL8940708 | 0.93 | PTPN11 (0.33) | GRIN1GRIN2BFASNFPR2S1PR1 | |
| SCHEMBL8932646 | 0.93 | GRIN1 (0.33) | GRIN1GRIN2BFPR2NAAAFGFR1 | |
| SCHEMBL8940704 | 0.93 | GRIN1 (0.36) | GRIN1GRIN2BFASNFPR2NAAA | |
| SCHEMBL8940718 | 0.93 | PTPN11 (0.35) | GRIN1GRIN2BFASNFPR2S1PR1 | |
| SCHEMBL8940828 | 0.93 | PTPN11 (0.35) | GRIN1GRIN2BFASNFPR2S1PR1 | |
| SCHEMBL8940777 | 0.93 | PTPN11 (0.35) | GRIN1GRIN2BFASNFPR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |