Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22272451 | 0.85 | PTPN1 (0.50) | PTPN1ACP1CDC25BMEN1POLB | |
| SCHEMBL21415445 | 0.78 | PTPN1 (0.43) | PTPN1CDC25B | |
| SCHEMBL21415456 | 0.76 | PIK3CD (0.32) | PTPN1 | |
| SCHEMBL21415447 | 0.76 | PTPN1 (0.45) | PTPN1ACP1CDC25BMEN1POLB | |
| SCHEMBL91068 | 0.74 | PTPN1 (0.43) | PTPN1ACP1CDC25BMAPTKMT2A | |
| SCHEMBL14572679 | 0.73 | PTPN1 (0.42) | PTPN1ACP1CDC25BMEN1POLB | |
| SCHEMBL13265137 | 0.73 | PTGS2 (0.31) | — | |
| SCHEMBL1587776 | 0.71 | ELANE (0.42) | KMT2AL3MBTL1NPSR1LMNA | |
| SCHEMBL8749165 | 0.71 | PTPN1 (0.41) | PTPN1ACP1CDC25B | |
| SCHEMBL14194485 | 0.71 | PTPN1 (0.57) | PTPN1ACP1CDC25BMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8176140-A | — | — | None | — | — | JP | disclosed |
| US-8466146-B2 | Cyclothiocarbamate derivatives as progesterone receptor modulators | WYETH LLC (US) | 2013-06-18 | — | — | US | disclosed |
| JP-H08176140-A | 5-METHYLENE-1,3-DIOXANE-4,6-DIONE DERIVATIVE, METHOD FOR SYNTHESIZING THE SAME AND METHOD FOR STABILIZING THE SAME | TOAGOSEI CO LTD | 1996-07-09 | — | — | JP | disclosed |