SCHEMBL8941764

SCHEMBL8941764

CC(=O)Oc1ccc2c(ccc3ccccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
ALDH1A1 P00352 1/20 0.57
HPGD P15428 1/20 0.57
PDGFRB P09619 1/20 0.51
FGFR1 P11362 1/20 0.51
PDGFRA P16234 1/20 0.51
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
TDP1 Q9NUW8 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 3/20 0.47
POLB P06746 2/20 0.47
GLA P06280 2/20 0.47
GAA P10253 1/20 0.47
ELANE P08246 1/20 0.47
CYP3A4 P08684 1/20 0.47
LMNA P02545 1/20 0.47
FLT3 P36888 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559115 1.00 MAPT (0.57) MAPTALDH1A1HPGDPDGFRBFGFR1
SCHEMBL995752 0.92 MAPT (0.51) MAPTALDH1A1HPGDPDGFRBFGFR1
SCHEMBL27497870 0.91 MAPT (0.50) MAPTALDH1A1HPGDPDGFRBFGFR1
SCHEMBL30439313 0.87 KMT2A (0.61) MAPTALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL30155392 0.87 KMT2A (0.61) MAPTALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL338523 0.87 KMT2A (0.61) MAPTALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL10437567 0.85 PDGFRB (0.56) MAPTALDH1A1PDGFRBFGFR1PDGFRA
Hydrochloric Acid SCHEMBL28481470 0.85 KMT2A (0.59) MAPTALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL28876060 0.85 PDGFRB (0.56) MAPTALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL27727266 0.85 KMT2A (0.59) MAPTALDH1A1PDGFRBFGFR1PDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8511812-B2 Aqueous ink composition and image forming method FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8511812-B2 Aqueous ink composition and image forming method FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20110109708-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-20110109708-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-20100216936-A1 PIGMENT COMPOSITION, METHOD OF PRODUCING WATER-BASED PIGMENT DISPERSION, WATER-BASED INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-08-26 US disclosed
US-20100216936-A1 PIGMENT COMPOSITION, METHOD OF PRODUCING WATER-BASED PIGMENT DISPERSION, WATER-BASED INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-08-26 US disclosed
US-5480913-A DIHYDRO-PHENANTHRENE DERIVATIVES, SIDE EFFECT REDUCTION ARCH DEVELOPMENT CORPORATION (US) 1996-01-02 US disclosed
EP-0363128-B1 ANTI-ANDROGEN COMPOUNDS ARCH DEVELOPMENT CORPORATION (US) 1993-09-01 EP disclosed
US-5208263-A Dihydrophenanthrene derivatives ARCH DEVELOPMENT CORPORATION (US) 1993-05-04 US disclosed
WO-1990003979-A2 ANTI-ANDROGEN COMPOUNDS ARCH DEVELOPMENT CORPORATION (US) 1990-04-19 WO disclosed
EP-0363128-A2 Anti-androgen compounds ARCH DEVELOPMENT CORPORATION (US) 1990-04-11 EP disclosed