Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497870 | 0.97 | MAPT (0.50) | MAPTALDH1A1HPGDNPSR1POLB | |
| SCHEMBL29559115 | 0.92 | MAPT (0.57) | MAPTALDH1A1HPGDNPSR1POLB | |
| SCHEMBL8941764 | 0.92 | MAPT (0.57) | MAPTALDH1A1HPGDNPSR1POLB | |
| SCHEMBL31458565 | 0.84 | TDP1 (0.51) | MAPTALDH1A1HPGDKDM4EGLA | |
| SCHEMBL30439313 | 0.82 | KMT2A (0.61) | MAPTALDH1A1POLBPDGFRBFGFR1 | |
| SCHEMBL30155392 | 0.82 | KMT2A (0.61) | MAPTALDH1A1POLBPDGFRBFGFR1 | |
| SCHEMBL338523 | 0.82 | KMT2A (0.61) | MAPTALDH1A1POLBPDGFRBFGFR1 | |
| SCHEMBL27945114 | 0.81 | KMT2A (0.71) | MAPTALDH1A1HPGDPOLBPDGFRB | |
| SCHEMBL28989640 | 0.81 | ELANE (0.53) | MAPTALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL10437567 | 0.80 | PDGFRB (0.56) | MAPTALDH1A1POLBNPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454270-A2 | LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS | Hetero Research Foundation (IN) | 2012-05-23 | — | — | EP | claimed |
| WO-2011007230-A2 | LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS | HETERO RESEARCH FOUNDATION (IN) | 2011-01-20 | — | — | WO | claimed |
| EP-3256483-A2 | C-3 NOVEL TRITERPENONE WITH C-28 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS | Hetero Labs Limited (IN) | 2017-12-20 | — | — | EP | disclosed |
| WO-2013160810-A2 | NOVEL BETULINIC ACID DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2013-10-31 | — | — | WO | disclosed |