Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941844 | 0.90 | GRM2 (0.57) | GRM2 | |
| SCHEMBL8942117 | 0.88 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9236212 | 0.88 | GRM2 (0.60) | GRM2 | |
| SCHEMBL8941939 | 0.87 | GRM2 (0.57) | GRM2 | |
| SCHEMBL8942024 | 0.86 | GRM2 (0.53) | GRM2 | |
| SCHEMBL8941850 | 0.85 | GRM2 (0.55) | GRM2 | |
| SCHEMBL2786197 | 0.85 | GRM2 (0.55) | GRM2 | |
| SCHEMBL6801533 | 0.85 | GRM2 (0.56) | GRM2 | |
| SCHEMBL2789355 | 0.84 | GRM2 (0.60) | GRM2 | |
| SCHEMBL9242572 | 0.79 | GRM2 (0.51) | GRM2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |