Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941993 | 0.91 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10OPRK1 | |
| SCHEMBL8942157 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10ADRB2 | |
| SCHEMBL8941980 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ADRB2 | |
| SCHEMBL8941943 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10ADRB2 | |
| SCHEMBL9786124 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7234823 | 0.82 | KMT2A (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8941916 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10OPRK1 | |
| SCHEMBL7228015 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7228640 | 0.80 | MEN1 (0.46) | KDM4EALDH1A1OPRK1KMT2AMEN1 | |
| SCHEMBL8942032 | 0.80 | DRD3 (0.41) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556861-A | 1,8 benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1996-09-17 | — | — | US | disclosed |