Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113455 | 0.85 | GRM2 (0.79) | GRM2 | |
| SCHEMBL8120087 | 0.83 | GRM2 (0.67) | GRM2 | |
| SCHEMBL8104770 | 0.78 | GRM2 (0.74) | GRM2 | |
| SCHEMBL8115869 | 0.78 | GRM2 (0.74) | GRM2 | |
| SCHEMBL8114180 | 0.78 | GRM2 (0.74) | GRM2 | |
| SCHEMBL8118809 | 0.77 | GRM2 (0.59) | GRM2 | |
| SCHEMBL2189810 | 0.75 | PTGIR (0.52) | — | |
| SCHEMBL5107348 | 0.75 | PTGIR (0.52) | — | |
| SCHEMBL7909523 | 0.74 | GRM2 (0.49) | GRM2MAPK1L3MBTL1 | |
| SCHEMBL2823430 | 0.73 | GRM2 (0.85) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |