Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160325 | 0.86 | GRM2 (0.62) | GRM2MAPK1L3MBTL1HTR2BHRH3 | |
| SCHEMBL24933695 | 0.85 | GRM2 (0.51) | GRM2MAPK1L3MBTL1HTR2BHRH3 | |
| SCHEMBL3372293 | 0.84 | GRM2 (0.63) | GRM2MAPK1L3MBTL1HTR2BHRH3 | |
| SCHEMBL11161832 | 0.82 | GRM2 (0.50) | GRM2MAPK1L3MBTL1HTR2BHRH3 | |
| SCHEMBL9636582 | 0.80 | GRM2 (0.47) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL9636573 | 0.80 | GRM2 (0.47) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL8120087 | 0.80 | GRM2 (0.67) | GRM2 | |
| SCHEMBL11154145 | 0.79 | GRM2 (0.46) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL10662236 | 0.78 | GRM2 (0.40) | GRM2MAPK1L3MBTL1HTR2B | |
| SCHEMBL8104770 | 0.77 | GRM2 (0.74) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061366-A1 | MANUFACTURE OF BISOPROLOL AND INTERMEDIATES THEREFOR | CORDEN PHARMA IP LIMITED (IE) | 2010-06-03 | — | — | WO | disclosed |