Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942373 | 1.00 | TDP1 (0.55) | TDP1TSHRALDH1A1MAPK1CYP3A4 | |
| SCHEMBL8942198 | 0.82 | APP (0.50) | TSHRATMMAPTAPP | |
| SCHEMBL8942199 | 0.82 | APP (0.50) | TSHRATMMAPTAPP | |
| SCHEMBL8942320 | 0.79 | CYP3A4 (0.47) | ALDH1A1CYP3A4CA2LMNAMAPT | |
| SCHEMBL8942315 | 0.79 | CYP3A4 (0.47) | ALDH1A1CYP3A4CA2LMNAMAPT | |
| SCHEMBL87501 | 0.77 | TSHR (0.77) | TDP1TSHRALDH1A1MAPK1CYP3A4 | |
| SCHEMBL226708 | 0.77 | TSHR (0.77) | TDP1TSHRALDH1A1MAPK1CYP3A4 | |
| SCHEMBL423544 | 0.77 | TSHR (0.77) | TDP1TSHRALDH1A1MAPK1CYP3A4 | |
| SCHEMBL19244383 | 0.76 | TDP1 (0.76) | TDP1TSHRALDH1A1MAPK1CYP3A4 | |
| SCHEMBL19244231 | 0.76 | TDP1 (0.76) | TDP1TSHRALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6279360-A | — | — | None | — | — | JP | disclosed |
| US-5516932-A | Halogenated cinnamic acids and esters thereof, processes for the preparation thereof and halogenated aryldiazonium salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| JP-H06279360-A | HALOGENATED CINNAMIC ACID AND ITS ESTER, PREPARATION THEREOF AND HALOGENATED ARYLDIAZONIUM SALT | HOECHST AG | 1994-10-04 | — | — | JP | disclosed |