Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942198 | 1.00 | APP (0.50) | APPATMHCAR2ESR1MAPT | |
| SCHEMBL8942320 | 0.86 | CYP3A4 (0.47) | HCAR2ESR1MAPT | |
| SCHEMBL8942315 | 0.86 | CYP3A4 (0.47) | HCAR2ESR1MAPT | |
| SCHEMBL8942374 | 0.82 | TDP1 (0.55) | APPATMMAPTTSHR | |
| SCHEMBL8942373 | 0.82 | TDP1 (0.55) | APPATMMAPTTSHR | |
| SCHEMBL585888 | 0.81 | APP (0.59) | APPATMHCAR2ESR1SMN1; SMN2 | |
| SCHEMBL585889 | 0.81 | APP (0.59) | APPATMHCAR2ESR1SMN1; SMN2 | |
| SCHEMBL6792876 | 0.78 | APP (0.53) | APPATMHCAR2MAPTRAB9A | |
| SCHEMBL6792878 | 0.78 | APP (0.53) | APPATMHCAR2MAPTRAB9A | |
| SCHEMBL12610085 | 0.78 | ATM (0.53) | APPATMHCAR2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516932-A | Halogenated cinnamic acids and esters thereof, processes for the preparation thereof and halogenated aryldiazonium salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |