Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942327 | 0.87 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL8349330 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8606874 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8942229 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8604839 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8605353 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8942506 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8942203 | 0.70 | DPP4 (0.43) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8607711 | 0.70 | GAA (0.64) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL8351298 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1HPGDPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | claimed |
| US-5482933-A | ANOXIA, ISCHEMIA | G. D. SEARLE & CO. (US) | 1996-01-09 | — | — | US | disclosed |
| US-5480876-A | FROM ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | disclosed |
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | disclosed |