Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150345 | 0.93 | CYP3A4 (0.50) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL8058942 | 0.86 | TDP1 (0.40) | CYP3A4LPAR3LPAR2TDP1TP53 | |
| SCHEMBL5852225 | 0.86 | LPAR3 (0.58) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL2150299 | 0.84 | LPAR3 (0.61) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL5852206 | 0.84 | LPAR3 (0.61) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL8044300 | 0.84 | LPAR3 (0.61) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL1149901 | 0.83 | — | — | |
| SCHEMBL11422055 | 0.78 | — | — | |
| SCHEMBL2150777 | 0.78 | LPAR2 (0.36) | CYP3A4LPAR3LPAR2TDP1TP53 | |
| SCHEMBL1604996 | 0.76 | MEN1 (0.54) | CYP3A4LPAR3LPAR2TDP1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536711-A | Bisphosphoryl hydrazines and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5536710-A | Bisphosphoryl hydrazines and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5536712-A | Bisphosphoryl hydrazines and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0437336-B1 | Biophosphoryl hydrazines and their use as pesticides | ROHM & HAAS (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5461038-A | Bisphosphoryl hydrazines and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0437335-A1 | Dithiopyrophosphates and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| EP-0437336-A1 | Biophosphoryl hydrazines and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| US-4474776-A | Anthryl substituted phosphorus compounds as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4474774-A | Acridone substituted phosphorus compounds, compositions containing same and insecticidal method of use | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4452792-A | Acridine substituted phosphorus compounds and their insecticidal use | VELSICOL CHEMICAL CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| US-4447420-A | Fluorenone esters of phosphoric and phosphonic acids as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4404220-A | INSECTIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4299772-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |