Methoxymethane

Methoxymethane

SCHEMBL8942495

COC.Nc1ccc(O)c(O)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.56
TSHR P16473 1/20 0.56
PDE10A Q9Y233 1/20 0.56
GAA P10253 4/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
ALOX15 P16050 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MAPK1 P28482 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PRKCI P41743 1/20 0.45
KDM4E B2RXH2 6/20 0.45
MAPT P10636 5/20 0.45
TDP1 Q9NUW8 5/20 0.45
ALDH1A1 P00352 4/20 0.45
RECQL P46063 4/20 0.45
CYP3A4 P08684 2/20 0.45
MEN1 O00255 2/20 0.45
THRB P10828 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL11239269 0.90 CASP1 (0.61) CASP1TSHRPDE10AGAACA1
SCHEMBL67890 0.89
SCHEMBL29557135 0.89
SCHEMBL27755355 0.87 CASP1 (0.56) CASP1TSHRPDE10AGAACA1
Hydrochloric Acid SCHEMBL11546195 0.87 CASP1 (0.56) CASP1TSHRPDE10AGAACA1
Bromide SCHEMBL17786298 0.87 CASP1 (0.56) CASP1TSHRPDE10AGAACA1
Methane SCHEMBL5491703 0.87 CASP1 (0.56) CASP1TSHRPDE10AGAACA1
Acetic Acid SCHEMBL27477102 0.81 KDM4E (0.57) CASP1TSHRPDE10AGAACA1
Ether SCHEMBL11153214 0.79 PRKCI (0.46) CASP1TSHRPDE10AGAACA1
Oxirane SCHEMBL11153217 0.78 CASP1 (0.48) CASP1TSHRPDE10AGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578711-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5541299-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-07-30 US disclosed
US-5502171-A Process for the preparation of dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
US-4529691-A Non-diffusible yellow coupler AGFA-GEVAERT AG (DE) 1985-07-16 US disclosed