Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942422 | 0.87 | HPGD (0.45) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| SCHEMBL8942212 | 0.84 | TBXA2R (0.45) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| Butylamine SCHEMBL8942217 | 0.78 | TBXA2R (0.45) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| SCHEMBL9233845 | 0.78 | PTGS1 (0.40) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| SCHEMBL8942431 | 0.76 | SMN1; SMN2 (0.54) | KDM4EALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8942460 | 0.76 | MAPT (0.56) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| SCHEMBL9307858 | 0.75 | HPGD (0.51) | KDM4EALDH1A1PTGS1PTGS2PIN1 | |
| SCHEMBL8942209 | 0.75 | MAPT (0.53) | KDM4EALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8942456 | 0.74 | SMN1; SMN2 (0.52) | KDM4EALDH1A1PTGS1PTGS2MEN1 | |
| Hydrochloric Acid SCHEMBL8942296 | 0.73 | SMN1; SMN2 (0.51) | KDM4EALDH1A1PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521311-A | USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0685461-A1 | 5-AMINOACETYLAMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-12-06 | — | — | EP | disclosed |