Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942542 | 1.00 | GLO1 (0.72) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL30172648 | 1.00 | GLO1 (0.72) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL8018753 | 0.88 | GLO1 (0.90) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL11097676 | 0.86 | GLO1 (0.77) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL11097674 | 0.86 | GLO1 (0.77) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL1095181 | 0.86 | GLO1 (0.73) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL1095182 | 0.86 | GLO1 (0.73) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL3043851 | 0.85 | GLO1 (0.72) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL1095183 | 0.85 | GLO1 (0.72) | GLO1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL7475824 | 0.84 | GLO1 (0.78) | GLO1ALDH1A1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572253-A | Synthesis process of manidipine hydrochloride raw material medicine | 许昌恒生制药有限公司 | 2023-01-06 | — | — | CN | disclosed |
| US-5569774-A | Process for the preparation of chlorine-substituted olefins | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |