Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942304 | 0.83 | RNF4 (0.58) | PDE4BKMT2AMEN1MAPK1MAPT | |
| SCHEMBL8942555 | 0.81 | KMT2A (0.49) | PDE4BKMT2AMEN1MAPK1MAPT | |
| SCHEMBL9574616 | 0.78 | SMN1; SMN2 (0.56) | PDE4BKMT2AMEN1MAPK1MAPT | |
| SCHEMBL9134025 | 0.78 | KMT2A (0.65) | KMT2AMEN1MAPTLMNAPKM | |
| SCHEMBL28893860 | 0.74 | PDE4B (0.63) | PDE4BKMT2AMEN1MAPK1MAPT | |
| SCHEMBL9012318 | 0.73 | POLB (0.47) | PDE4BKMT2AMEN1MAPK1MAPT | |
| SCHEMBL8828057 | 0.72 | POLB (0.73) | KMT2AMEN1MAPTPKMSMN1; SMN2 | |
| SCHEMBL12793749 | 0.72 | KMT2A (0.76) | KMT2AMEN1MAPK1MAPTHSD17B10 | |
| SCHEMBL24909301 | 0.72 | KMT2A (0.61) | KMT2AMEN1MAPK1MAPTHSD17B10 | |
| SCHEMBL4179176 | 0.72 | KMT2A (0.60) | KMT2AMEN1MAPK1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521311-A | USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0685461-A1 | 5-AMINOACETYLAMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-12-06 | — | — | EP | disclosed |