Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012618 | 0.82 | CYP19A1 (0.51) | POLBATML3MBTL1PDE4BSMN1; SMN2 | |
| SCHEMBL8942304 | 0.79 | RNF4 (0.58) | POLBPDE4BCCR2PTGDR2SMN1; SMN2 | |
| SCHEMBL9574616 | 0.79 | SMN1; SMN2 (0.56) | POLBPDE4BCCR2PTGDR2SMN1; SMN2 | |
| SCHEMBL8942553 | 0.73 | PDE4B (0.54) | PDE4BSMN1; SMN2LMNAMEN1MAPK1 | |
| SCHEMBL10696227 | 0.72 | HDAC8 (0.60) | HDAC1HDAC2MEN1KMT2AMAPT | |
| SCHEMBL10417277 | 0.71 | PTGS1 (0.55) | CCR2PTGDR2SMN1; SMN2PTGS2LMNA | |
| SCHEMBL28893860 | 0.70 | PDE4B (0.63) | POLBPDE4BSMN1; SMN2PTGS2LMNA | |
| SCHEMBL10415462 | 0.70 | NR3C1 (0.52) | CCR2PTGDR2SMN1; SMN2PTGS2LMNA | |
| SCHEMBL8524539 | 0.70 | TTR (0.56) | CCR2PTGDR2SMN1; SMN2PTGS2LMNA | |
| SCHEMBL5131381 | 0.70 | HDAC8 (0.63) | HDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645374-B1 | 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5449826-A | Antiinflammatory, antipyretic, antirheumatic, and analgesic agents | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0645374-A1 | 5-AMINO-2-PHENOXYSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-29 | — | — | EP | disclosed |