SCHEMBL8942593

SCHEMBL8942593

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OCCCC)c(F)c4F)cc3)c(F)c2F)OC1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
FPR2 P25090 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942805 0.99 PTPN11 (0.30) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8942560 0.98 FPR2 (0.32) FPR2
SCHEMBL8942568 0.97 FPR2 (0.32) FPR2
SCHEMBL8942559 0.97 FPR2 (0.32) FPR2
SCHEMBL8942737 0.97 FPR2 (0.32) FPR2
SCHEMBL8942698 0.97 FPR2 (0.32) FPR2
SCHEMBL8942552 0.97 FPR2 (0.33) FPR2
SCHEMBL8942804 0.97 FPR2 (0.32) FPR2
SCHEMBL8942823 0.97 FPR2 (0.32) FPR2
SCHEMBL8942244 0.97 FPR2 (0.32) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed