Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942912 | 0.91 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL8942932 | 0.88 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8942847 | 0.87 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8942719 | 0.87 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8847572 | 0.81 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL8847837 | 0.81 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8847539 | 0.80 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9095621 | 0.80 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL4562990 | 0.80 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL7308690 | 0.80 | AGTR1 (0.79) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521177-A | ANGIOTENSIN ANTAGONIST FOR CARDIOVASCULAR DISORDERS SUCH AS ISCHEMIA OR CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS COGNITIVE FUNCTIONS, DEPRESSION, ALZHEIMER'S DISEASE OR PARKINSON'S SYNDROME | DR. KARL THOMAE GMBH (DE) | 1996-05-28 | — | — | US | disclosed |