Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.39 |
| ▸ | HTR3B | O95264 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58110 | 0.86 | TDP1 (0.55) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| SCHEMBL29537333 | 0.82 | CYP3A4 (0.52) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| SCHEMBL93270 | 0.82 | CYP3A4 (0.52) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| Hydrochloric Acid SCHEMBL9078906 | 0.80 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| Hydrochloric Acid SCHEMBL9078903 | 0.80 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| Methane SCHEMBL27995664 | 0.80 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| SCHEMBL8594415 | 0.80 | TDP1 (0.76) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| SCHEMBL2782331 | 0.80 | TDP1 (0.53) | TDP1MAPK1CYP3A4TRPA1HTR3E | |
| SCHEMBL671741 | 0.79 | CYP3A4 (0.54) | TDP1MAPK1CYP3A4TRPA1ALDH1A1 | |
| SCHEMBL6999020 | 0.79 | CYP3A4 (0.48) | TDP1MAPK1CYP3A4TRPA1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710257-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL CO (US) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003346-A1 | IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS | SHELL OIL COMPANY (US) | 1995-02-02 | — | — | WO | disclosed |