SCHEMBL58110

SCHEMBL58110

O=C=Nc1cccc(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
MAPK1 P28482 1/20 0.55
HTR3E A5X5Y0 2/20 0.48
HTR3B O95264 2/20 0.48
HTR3A P46098 2/20 0.48
HTR3D Q70Z44 2/20 0.48
HTR3C Q8WXA8 2/20 0.48
SLC22A2 O15244 1/20 0.48
SLC22A1 O15245 1/20 0.48
SLC22A3 O75751 1/20 0.48
PLAU P00749 1/20 0.48
MAPT P10636 4/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 4/20 0.43
CYP3A4 P08684 4/20 0.43
MEN1 O00255 3/20 0.43
CYP2D6 P10635 2/20 0.43
TSHR P16473 2/20 0.43
CYP2C9 P11712 1/20 0.43
THPO P40225 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2782331 0.92 TDP1 (0.53) TDP1MAPK1HTR3EHTR3BHTR3A
SCHEMBL8594415 0.89 TDP1 (0.76) TDP1MAPK1HTR3EHTR3BHTR3A
SCHEMBL8942771 0.86 TDP1 (0.47) TDP1MAPK1HTR3EHTR3BHTR3A
SCHEMBL10615043 0.84 TDP1 (0.54) TDP1MAPK1MAPTGAAKMT2A
SCHEMBL27873 0.84 TDP1 (0.54) TDP1MAPK1MAPTGAAKMT2A
SCHEMBL11430455 0.82 HTR3E (0.52) TDP1HTR3EHTR3BHTR3AHTR3D
SCHEMBL27621561 0.81 TDP1 (0.52) TDP1MAPK1CYP3A4TSHRTRPA1
Chlorobenzene SCHEMBL27462549 0.80 TSHR (0.50) TDP1MAPK1MAPTGAAKMT2A
Ethylene SCHEMBL10425506 0.79 TDP1 (0.50) TDP1MAPK1CYP3A4TSHRTRPA1
Chlorobenzene SCHEMBL28207890 0.79 MAPK1 (0.47) TDP1MAPK1HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2255 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-118459291-B Bionic dynamic self-healing super-hydrophobic bio-based coated controlled release fertilizer and preparation method thereof 山东农业大学 2025-02-07 CN claimed
CN-119161580-A Amide group-containing polydisulfide degradable high polymer material and preparation method thereof 衢州化工新材料创新研究院 2024-12-20 CN claimed
CN-115960017-B Modified acrylic ester monomer and photo-curable resin thereof 上海华峰龙湾技术有限公司 2024-11-22 CN claimed
CN-118459291-A Bionic dynamic self-healing super-hydrophobic bio-based coated controlled release fertilizer and preparation method thereof 山东农业大学 2024-08-09 CN claimed
CN-114551885-B Black adhesive for lithium battery aluminum plastic film and use method thereof 上海紫江新材料科技股份有限公司 2024-06-11 CN claimed
CN-117285890-A Preparation method of formaldehyde-free environment-friendly flame-retardant plywood 南宁市匠心鸣居建筑材料有限公司 2023-12-26 CN claimed
CN-116768764-A Process for preparing urea derivatives 安道麦阿甘有限公司 2023-09-19 CN claimed
CN-111471171-B Arylsulfonic acid intermediate, preparation method thereof and application of aryl sulfonic acid intermediate in synthesizing low-temperature-sensitivity additive for concrete 江苏苏博特新材料股份有限公司 2023-07-18 CN claimed
CN-115960017-A Modified acrylate monomer and photocurable resin thereof 上海华峰龙湾技术有限公司 2023-04-14 CN claimed
WO-2009114856-A2 AURORA KINASE INHIBITORS SUNESIS PHARMACEUTICALS, INC. (US) 2009-09-17 WO claimed
WO-2008156559-A2 TOPICAL DENTAL SOLUTION OF CHLORHEXIDINE IN SUMATRA BENZOIN BP/EP AND METHODS OF MANUFACTURING AND EVALUATING SAME CHX TECHNOLOGIES, INC. (CA) 2008-12-24 WO claimed
US-20070249823-A1 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2007-10-25 US claimed
WO-2007070804-A2 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2007-06-21 WO claimed
EP-1754705-A2 Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders Genentech, Inc. (US) 2007-02-21 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-5229243-A Addition polymer core, polyurethane or polythiourethane shell KAO CORPORATION (JP) 1993-07-20 US claimed
US-4359426-A Process for the production of aromatic isocyanates containing aromatically bound sulfochloride groups BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US claimed
EP-0034711-A2 Process for preparing aromatic isocyanates with aromatically bound sulfochloride groups BAYER AG (DE) 1981-09-02 EP claimed
US-4138422-A UREAS AND CARBAMATES FROM ISOCYANATES ON AN INERT SOLID GRANULAR MATERIAL UNION CARBIDE CORPORATION (US) 1979-02-06 US claimed