SCHEMBL8942822

SCHEMBL8942822

Oc1cc2cc3ccccc3cc2cc1-n1cnc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 5/20 0.50
HTT P42858 3/20 0.47
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.44
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ROCK1 Q13464 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
SRC P12931 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942815 0.97 FGFR1 (0.53) FGFR1HTTALDH1A1POLBKDM4E
SCHEMBL56852 0.79 FGFR1 (0.61) FGFR1HTTALDH1A1POLBHPGD
SCHEMBL8624088 0.77 FGFR1 (0.59) FGFR1HTTALDH1A1POLBHPGD
SCHEMBL29054311 0.77 GSR (0.49) FGFR1HTTALDH1A1POLBROCK1
SCHEMBL30955940 0.75 HTT (0.50) FGFR1HTTALDH1A1POLBROCK1
SCHEMBL3417306 0.74 HTT (0.73) FGFR1HTTALDH1A1POLBROCK1
SCHEMBL28915831 0.74 FGFR1 (0.51) FGFR1HTTALDH1A1POLBROCK1
SCHEMBL6294146 0.74 FGFR1 (0.62) FGFR1HTTALDH1A1POLBKDM4E
SCHEMBL17351699 0.72 FGFR1 (0.62) FGFR1HTTPOLBROCK1MKNK1
SCHEMBL30955935 0.71 HCAR1 (0.56) FGFR1HTTPOLBROCK1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501927-A DISAZO OR TRISAZO DYES FUJI XEROX CO., LTD. (JP) 1996-03-26 US disclosed