SCHEMBL8942876

SCHEMBL8942876

O=C(Oc1cc[c]cc1)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
ATM Q13315 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX15 P16050 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 2/20 0.41
PPARG P37231 1/20 0.41
NCOA2 Q15596 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NSD2 O96028 1/20 0.40
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 1/20 0.39
ELANE P08246 1/20 0.38
CYP19A1 P11511 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023018 0.91 TDP1 (0.44) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL18073 0.86 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL27352197 0.86 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9241160 0.86 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9353461 0.86 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9353455 0.86 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL10945396 0.84 TDP1 (0.52) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL1362173 0.84 TDP1 (0.52) TDP1ATML3MBTL1ALOX15HPGD
Bicarbonate SCHEMBL21879667 0.84 TDP1 (0.52) TDP1ATML3MBTL1ALOX15HPGD
Bicarbonate SCHEMBL9240263 0.84 TDP1 (0.52) TDP1ATML3MBTL1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4068085-A YELLOW AND RED ON POLYESTERS AND ACRYLICS CIBA-GEIGY CORPORATION (US) 1978-01-10 US claimed
CN-115697716-A On-press developable lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2023-02-03 CN disclosed
CN-115666959-A On-press developable lithographic printing plate precursor, method for producing lithographic printing plate, and lithographic printing method 富士胶片株式会社 2023-01-31 CN disclosed
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed