SCHEMBL8942893

SCHEMBL8942893

Cc1cc(Cl)c2c(c1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.70
CYP1A2 P05177 1/20 0.70
ADORA2A P29274 2/20 0.49
IDO1 P14902 1/20 0.48
DNMT1 P26358 1/20 0.48
DNMT3L Q9UJW3 1/20 0.48
DNMT3A Q9Y6K1 1/20 0.48
TTR P02766 4/20 0.46
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 3/20 0.43
ELANE P08246 2/20 0.43
TSHR P16473 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CASP3 P42574 1/20 0.43
HBB P68871 1/20 0.43
SENP7 Q9BQF6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905734 0.82 CYP1A1 (0.56) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL11853447 0.82 MEN1 (0.56) CYP1A1CYP1A2IDO1DNMT1DNMT3L
SCHEMBL3581453 0.82 CYP1A1 (1.00) CYP1A1CYP1A2ADORA2ATTRALDH1A1
SCHEMBL8876460 0.78 CYP1A1 (0.60) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL2767533 0.77 ADORA2A (0.67) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL10340740 0.76 ALDH1A1 (0.62) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL308115 0.75 ADORA2A (0.76) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL6904553 0.75 IDO1 (0.59) CYP1A1CYP1A2ADORA2AIDO1DNMT1
Dichlon SCHEMBL9820419 0.75 IDO1 (0.67) CYP1A1CYP1A2ADORA2AIDO1DNMT1
SCHEMBL11222115 0.74 TTR (0.58) CYP1A1CYP1A2ADORA2AIDO1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5585454-A Poly(quinone) and preparation and use of same TOKYO INSTITUTE OF TECHNOLOGY (JP) 1996-12-17 US disclosed