SCHEMBL8942906

SCHEMBL8942906

Brc1ccc2ocnc2c1.Fc1ccc2ocnc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 4/20 0.46
WNT3A P56704 4/20 0.46
DYRK1A Q13627 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CLK1 P49759 1/20 0.35
CLK2 P49760 1/20 0.35
CLK3 P49761 1/20 0.35
GSK3B P49841 1/20 0.35
CDK9 P50750 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
PIK3CA P42336 3/20 0.35
PIK3R1 P27986 1/20 0.35
GABRP O00591 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17068937 0.89 CTNNB1 (0.53) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL29372420 0.89 CTNNB1 (0.53) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL1585861 0.89 CTNNB1 (0.53) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL29748409 0.89 DYRK1A (0.49) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL10486 0.89 DYRK1A (0.49) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL8080835 0.75 DYRK1A (0.60) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL645873 0.75 DYRK1A (0.60) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL10842 0.74 DYRK1A (0.49) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL1798498 0.74 DYRK1A (0.49) CTNNB1WNT3ADYRK1AMEN1ALDH1A1
SCHEMBL31597223 0.71 CTNNB1 (0.37) CTNNB1WNT3ADYRK1AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491057-A FREE FROM FLUCTUATION OF SENSITIVITY UNDER SPONTANEOUS STORAGE FUJI PHOTO FILM CO., LTD. (JP) 1996-02-13 US disclosed