SCHEMBL10486

SCHEMBL10486

Brc1ccc2ocnc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.49
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
CTNNB1 P35222 4/20 0.42
WNT3A P56704 4/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PIK3R1 P27986 1/20 0.41
PIK3CA P42336 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
PABPC1 P11940 1/20 0.38
AHR P35869 3/20 0.38
TRPM5 Q9NZQ8 1/20 0.37
NAMPT P43490 1/20 0.37
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29748409 1.00 DYRK1A (0.49) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL8942906 0.89 CTNNB1 (0.46) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL8080835 0.84 DYRK1A (0.60) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL10842 0.83 DYRK1A (0.49) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL11781360 0.79 CYP2A6 (0.41) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL28048555 0.77 DYRK1A (0.72) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL27130686 0.75 DYRK1A (0.46) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL3816259 0.74 DYRK1A (0.49) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL5760474 0.74 DYRK1A (0.49) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL21937994 0.74 DYRK1A (0.49) DYRK1AMEN1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117926287-A Method for synthesizing 2-aminobenzoxazole derivative under electrochemical condition 湘潭大学 2024-04-26 CN claimed
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4154616-A BENZOXAZOLE OR NAPHTHOXAZOLE MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-15 US claimed
US-4057430-A MEROCYANINE THIOHYDANTOIN SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1977-11-08 US claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-20260060961-A1 SUBSTITUTED HETEROCYCLES AS RAS INHIBITORS JAZZ PHARMACEUTICALS IRELAND LTD (IE) 2026-03-05 US disclosed
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US disclosed
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3953216-A BENZOXAZOLES, NAPHTHOXAZOLES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060961-A1 SUBSTITUTED HETEROCYCLES AS RAS INHIBITORS KRAS, NRAS, HRAS DYRK1A 1222/4885MEN1 977/4885ALDH1A1 1940/4885
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 DYRK1A 967/4885MEN1 2735/4885ALDH1A1 2169/4885
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK DYRK1A 1637/4885MEN1 3220/4885ALDH1A1 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.