SCHEMBL8942999

SCHEMBL8942999

CCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1F

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.74
RARB P10826 5/20 0.64
THRA P10827 1/20 0.58
THRB P10828 1/20 0.58
ALDH1A1 P00352 1/20 0.57
HPGD P15428 1/20 0.57
TP53 P04637 1/20 0.57
TSHR P16473 1/20 0.57
PTPN1 P18031 1/20 0.56
PTPN6 P29350 1/20 0.56
PLA2G2D Q9UNK4 1/20 0.56
PLA2G4B P0C869 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9387467 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL15284776 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL9626934 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL9627343 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL9627701 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL9627749 1.00 PTPN11 (0.74) PTPN11RARBTHRATHRBALDH1A1
Hydrochloric Acid SCHEMBL9650980 0.99 PTPN11 (0.73) PTPN11RARBTHRATHRBALDH1A1
Hydrochloric Acid SCHEMBL9440590 0.99 PTPN11 (0.73) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL9437150 0.90 THRA (0.68) PTPN11RARBTHRATHRBALDH1A1
SCHEMBL15731804 0.90 THRA (0.68) PTPN11RARBTHRATHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0341686-B1 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORP (JP) 1994-08-17 EP disclosed
US-5232625-A Cyano-alicyclic esters in liquid crystal compositions THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1993-08-03 US disclosed
US-5230830-A Ferroelectricity THE SECRTEARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1993-07-27 US disclosed
EP-0391956-B1 CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES SECR DEFENCE BRIT (GB) 1993-04-21 EP disclosed
US-5147577-A Ferroelectric THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-09-15 US disclosed
EP-0357702-B1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK PATENT GmbH (DE) 1992-08-12 EP disclosed
US-5133896-A Cyanohyorin derivatives and their use in liquid crystal materials and devices THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1992-07-28 US disclosed
EP-0280419-B1 OPTICALLY ACTIVE-2-SUBSTITUTED-PROPYL ETHER AND LIQUID CRYSTAL COMPOSITION Chisso Corporation (JP) 1992-07-08 EP disclosed
EP-0368975-A1 FLUORINATED BIPHENYLDIOLE DERIVATIVES. MERCK PATENT GMBH (DE) 1990-05-23 EP disclosed
EP-0357702-A1 FLUORINATED OLIGOPHENYL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-03-14 EP disclosed
WO-1989012039-A1 FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-12-14 WO disclosed
EP-0341686-A2 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORPORATION (JP) 1989-11-15 EP disclosed
EP-0333760-A1 CYANO-ALICYCLIC ESTERS AND LIQUID CRYSTAL COMPOSITIONS. SECR DEFENCE BRIT (GB) 1989-09-27 EP disclosed
WO-1989006678-A1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed
WO-1989005792-A1 CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1989-06-29 WO disclosed
US-4828754-A TILT-TYPE CHIRAL SMECTIC PHASE DAINIPPON INK & CHEMICALS, INC. (JP) 1989-05-09 US disclosed
WO-1988004290-A1 CYANO-ALICYCLIC ESTERS IN LIQUID CRYSTAL COMPOSITIONS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1988-06-16 WO disclosed
EP-0188222-A2 Novel liquid cristalline compounds having substituents DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-07-23 EP disclosed