Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942705 | 0.87 | AGTR1 (0.46) | AGTR1PPARG | |
| SCHEMBL8942979 | 0.86 | AGTR1 (0.42) | AGTR1PPARG | |
| SCHEMBL8942684 | 0.84 | PPARG (0.42) | AGTR1PPARG | |
| SCHEMBL8942664 | 0.84 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL8942667 | 0.84 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL8943169 | 0.83 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8943174 | 0.83 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8943194 | 0.82 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8943192 | 0.82 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8942718 | 0.82 | AGTR1 (0.52) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521177-A | ANGIOTENSIN ANTAGONIST FOR CARDIOVASCULAR DISORDERS SUCH AS ISCHEMIA OR CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS COGNITIVE FUNCTIONS, DEPRESSION, ALZHEIMER'S DISEASE OR PARKINSON'S SYNDROME | DR. KARL THOMAE GMBH (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0591891-A2 | Benzimidazole derivatives as Angiotensin II antagonists | Dr. Karl Thomae GmbH (DE) | 1994-04-13 | — | — | EP | disclosed |