Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MGAM | O43451 | 4/20 | 0.43 |
| ▸ | SI | P14410 | 4/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615316 | 0.89 | NPC1 (0.61) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL9284642 | 0.89 | NPC1 (0.61) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL9284657 | 0.88 | MAPT (0.48) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9337494 | 0.87 | MAPT (0.44) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL9618725 | 0.81 | GAA (0.44) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL3421079 | 0.80 | GAA (0.55) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL10451577 | 0.80 | ALDH1A1 (0.39) | MAOBMAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL261038 | 0.78 | CA12 (0.53) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL9551295 | 0.77 | NPC1 (0.57) | NPC1MEN1KMT2ARAB9AALDH2 | |
| SCHEMBL8943415 | 0.77 | NPC1 (0.45) | NPC1MEN1KMT2ARAB9AALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4297462-A | — | — | None | — | — | JP | disclosed |
| EP-0467721-B1 | Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same | MITSUBISHI RAYON CO (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5480580-A | COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY | MITSUBISHI RAYON COMPANY LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5395553-A | Liquid crystalline compounds, liquid crystal compositions containing the same and use thereof | DAISO CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0410447-B1 | Liquid crystalline compounds, liquid crystal compositions containing the same and use thereof | DAISO CO LTD (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5338482-A | Liquid crystalline compounds, liquid crystal compositions containing the same and use thereof | DAISO CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5324450-A | Stable optically active glycidyl ether derivatives | DAISO CO., LTD. (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5308540-A | REACTING AN OPTICALLY ACTIVE GLYCIDYL ETHER WITH A MALONATE IN THE PRESENCE OF A BASE IN AN ORGANIC SOLVENT TO PRODUCE A COMPOUND HAVING AN OPTICALLY ACTIVE LACTONE RING | DAISO CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0355830-B1 | Liquid crystal composition and use thereof | DAISO CO LTD (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0306919-B1 | LIQUID CRYSTALLINE COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF | DAISO CO., LTD. (JP) | 1993-02-17 | — | — | EP | disclosed |
| JP-H04297462-A | PYRIMIDINE DERIVATIVE | MITSUBISHI KASEI CORP | 1992-10-21 | — | — | JP | disclosed |
| EP-0467721-A1 | Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same | MITSUBISHI RAYON CO., LTD (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0410447-A2 | Liquid crystalline compounds, liquid crystal compositions containing the same and use thereof | DAISO CO., LTD. (JP) | 1991-01-30 | — | — | EP | disclosed |
| US-4973425-A | ELECTROOPTICS | DAISO CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4909957-A | Containing lactone ring structure | DAISO CO., LTD. (JP) | 1990-03-20 | — | — | US | disclosed |