SCHEMBL8943309

SCHEMBL8943309

CS(=O)(=O)c1ccc(C(=O)C2=C(S(=O)(=O)c3ccccc3)C3CCC(C3)C2=O)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR6 P46095 1/20 0.41
MAPT P10636 3/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
CACNA1B Q00975 2/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.38
USP28 Q96RU2 5/20 0.38
SMO Q99835 2/20 0.37
ALB P02768 1/20 0.37
HTR1A P08908 1/20 0.37
SLC6A2 P23975 1/20 0.37
PDE4A P27815 1/20 0.37
OPRM1 P35372 1/20 0.37
DRD3 P35462 1/20 0.37
HTR2B P41595 1/20 0.37
SLC6A3 Q01959 1/20 0.37
PDE4D Q08499 1/20 0.37
SHH Q15465 1/20 0.37
SLC29A1 Q99808 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117919 0.82 MEN1 (0.41) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL24193281 0.82 MEN1 (0.41) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL30176818 0.77 CACNA1B (0.37) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8943326 0.77 SMO (0.38) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8943532 0.76 PDE4B (0.41) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8943536 0.76 PDE4B (0.41) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8943161 0.75 ALDH1A1 (0.52) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8577540 0.75 MEN1 (0.34) GPR6MAPTGAARAB9ACACNA1B
SCHEMBL8577544 0.75 MEN1 (0.34) GPR6MAPTGAARAB9ACACNA1B
3,6 Dichloromethoxybenzoic Acid SCHEMBL17927130 0.73 ALDH1A1 (0.38) GPR6CACNA1BNR1I2LMNAUSP28

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525580-A USED TO PREVENT WEEDS IN PADDY FIELDS SDS BIOTECH K.K. (JP) 1996-06-11 US disclosed