Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943604 | 0.99 | RARB (0.34) | ALOX5FASNRARBCYP3A4CYP2C9 | |
| SCHEMBL8943916 | 0.93 | ALOX5 (0.35) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8943437 | 0.93 | ALOX5 (0.35) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8943343 | 0.93 | ALOX5 (0.35) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8943113 | 0.93 | ALOX5 (0.35) | ALOX5FASNCYP3A4CYP2C9APP | |
| SCHEMBL18718626 | 0.93 | ALOX5 (0.35) | ALOX5EPHX1PPARGCYP1A2GRM2 | |
| SCHEMBL8943727 | 0.92 | RARB (0.36) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8943434 | 0.92 | RARB (0.36) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8944253 | 0.92 | RARB (0.36) | ALOX5FASNRARBEPHX1 | |
| SCHEMBL8943907 | 0.92 | ALOX5 (0.34) | ALOX5FASNRARBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |