SCHEMBL8943534

SCHEMBL8943534

CCOC(=O)C(Oc1nc(OC)nc(OC)n1)C(C)(C)OCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 12/20 0.41
EDNRA P25101 12/20 0.41
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CTSK P43235 1/20 0.39
POLB P06746 4/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NR1I2 O75469 1/20 0.32
KCNE1 P15382 1/20 0.32
KCNQ1 P51787 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943528 0.87 EDNRB (0.50) EDNRBEDNRAPOLBKMT2ANR1I2
SCHEMBL9558022 0.86 EDNRB (0.57) EDNRBEDNRA
SCHEMBL8943510 0.84 EDNRB (0.47) EDNRBEDNRAALDH1A1KMT2A
SCHEMBL8534495 0.73 EDNRB (0.68) EDNRBEDNRA
SCHEMBL9590496 0.71 EDNRB (0.56) EDNRBEDNRA
SCHEMBL9702107 0.70 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2CTSKPOLBTSHR
SCHEMBL8943339 0.70 EDNRB (0.35) EDNRBEDNRAALDH1A1SMN1; SMN2CTSK
SCHEMBL9367576 0.69 EDNRB (0.46) EDNRBEDNRAPOLBNR1I2KCNE1
SCHEMBL8535045 0.67 EDNRB (0.51) EDNRBEDNRA
SCHEMBL9367453 0.67 EDNRB (0.44) EDNRBEDNRAALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0517215-A1 Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1992-12-09 EP claimed
JP-5148245-A None JP disclosed
US-5529977-A A 3-ALKOXYBUTYRYLIMIDAZOLE COMPOUND UBE INDUSTRIES, LTD. (JP) 1996-06-25 US disclosed
US-5387575-A Pyrimidine derivatives, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1995-02-07 US disclosed
JP-H05148245-A TRIAZINE DERIVATIVE, ITS PRODUCTION AND HERBICIDE UBE IND LTD 1993-06-15 JP disclosed
EP-0517215-A1 Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1992-12-09 EP disclosed