SCHEMBL8943565

SCHEMBL8943565

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2)CO1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 11/20 0.37
SLC6A4 P31645 11/20 0.37
SLC6A3 Q01959 11/20 0.37
FPR2 P25090 7/20 0.37
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943998 0.99 FPR2 (0.36) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8943659 0.93 FPR2 (0.38) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL18718699 0.93 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8943442 0.93 FPR2 (0.35) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL18718708 0.92 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL18718709 0.92 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8943493 0.92 FPR2 (0.34) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8943870 0.92 FPR2 (0.35) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8944006 0.92 FPR2 (0.35) SLC6A2SLC6A4SLC6A3FPR2ALOX5
SCHEMBL8944113 0.91 FPR2 (0.35) SLC6A2SLC6A4SLC6A3FPR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed