SCHEMBL8943689

SCHEMBL8943689

COc1ccc(N(c2ccccc2)c2ccc(SC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.53
CYP1A1 P04798 3/20 0.53
CYP1B1 Q16678 3/20 0.53
CA4 P22748 1/20 0.45
LTA4H P09960 2/20 0.44
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
SLC6A4 P31645 2/20 0.41
KMT2A Q03164 1/20 0.41
QPCT Q16769 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
TRPA1 O75762 1/20 0.40
ALOX5 P09917 1/20 0.40
HTR2A P28223 1/20 0.40
KCNH2 Q12809 1/20 0.40
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12683362 0.95 CYP1A1 (0.49) CYP1A2CYP1A1CYP1B1CA4LTA4H
SCHEMBL8943756 0.93 CYP1A1 (0.60) CYP1A2CYP1A1CYP1B1ALDH1A1GAA
SCHEMBL8943768 0.93 CYP1A1 (0.60) CYP1A2CYP1A1CYP1B1ALDH1A1GAA
SCHEMBL8943632 0.87 CA4 (0.46) CA4LTA4HALDH1A1KDM4EHPGD
SCHEMBL13832978 0.87 CYP1A1 (0.55) CYP1A2CYP1A1CYP1B1ALDH1A1GAA
SCHEMBL10065630 0.87 CA4 (0.59) CYP1A2CA4LTA4HALDH1A1KDM4E
SCHEMBL13720711 0.87 CA4 (0.59) CYP1A2CA4LTA4HALDH1A1KDM4E
SCHEMBL13720596 0.87 CA4 (0.59) CYP1A2CA4LTA4HALDH1A1KDM4E
SCHEMBL21173484 0.87 ALDH1A1 (0.50) CYP1A2ALDH1A1KDM4ESLC6A4KMT2A
SCHEMBL13720899 0.87 CA4 (0.59) CYP1A2CA4LTA4HALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed