SCHEMBL8943696

SCHEMBL8943696

CCCCOc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.66
KCNA3 P22001 1/20 0.52
CYP2D6 P10635 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP19A1 P11511 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MLNR O43193 1/20 0.49
NR1I2 O75469 1/20 0.49
ESR1 P03372 1/20 0.49
NR3C1 P04150 1/20 0.49
PGR P06401 1/20 0.49
ADRB2 P07550 1/20 0.49
CHRM2 P08172 1/20 0.49
ADRB1 P08588 1/20 0.49
HTR1A P08908 1/20 0.49
ADRA2A P08913 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
DRD2 P14416 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31258518 1.00 LTA4H (0.66) LTA4HKCNA3CYP2D6CYP1A2CYP19A1
SCHEMBL8943730 1.00 LTA4H (0.66) LTA4HKCNA3CYP2D6CYP1A2CYP19A1
SCHEMBL31258519 1.00 LTA4H (0.66) LTA4HKCNA3CYP2D6CYP1A2CYP19A1
SCHEMBL8321594 0.96 LTA4H (0.68) LTA4HKCNA3MLNRNR1I2ESR1
SCHEMBL8943815 0.94 LTA4H (0.66) LTA4HKCNA3MLNRNR1I2ESR1
SCHEMBL8944298 0.94 LTA4H (0.59) LTA4HKCNA3CYP2D6CYP1A2CYP19A1
SCHEMBL8943752 0.94 LTA4H (0.66) LTA4HKCNA3MLNRNR1I2ESR1
SCHEMBL10883851 0.94 LTA4H (0.59) LTA4HCYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL31229476 0.94 LTA4H (0.66) LTA4HKCNA3MLNRNR1I2ESR1
SCHEMBL16968357 0.94 LTA4H (0.66) LTA4HKCNA3MLNRNR1I2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735032-B2 Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-05-27 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed