Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057744 | 0.96 | TDP1 (0.47) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1822785 | 0.92 | TDP1 (0.56) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10025035 | 0.91 | TDP1 (0.44) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8943687 | 0.90 | CYP3A4 (0.46) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8943906 | 0.88 | ALDH1A1 (0.47) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL2856507 | 0.87 | CYP3A4 (0.44) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14645485 | 0.87 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL13321986 | 0.87 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1356320 | 0.86 | ALDH1A1 (0.50) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1357035 | 0.86 | ALDH1A1 (0.50) | TDP1CYP3A4ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480765-A | PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |