SCHEMBL8943796

SCHEMBL8943796

O=C(OCc1c2ccccc2cc2ccccc12)c1ccc(C(=O)OCc2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
KMT2A Q03164 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
LMNA P02545 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
L3MBTL1 Q9Y468 4/20 0.48
MAPK1 P28482 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
PPARG P37231 1/20 0.47
APAF1 O14727 1/20 0.47
CDC25B P30305 1/20 0.47
CASP3 P42574 1/20 0.47
CASP6 P55212 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
ATM Q13315 1/20 0.45
MEN1 O00255 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4648309 0.95 TDP1 (0.56) EPHX1KMT2ATDP1LMNASLC6A2
SCHEMBL8371950 0.92 RXFP1 (0.57) EPHX1KMT2ATDP1LMNAL3MBTL1
SCHEMBL17323590 0.89 EPHX1 (0.44) EPHX1KMT2ATDP1LMNASLC6A2
SCHEMBL14277072 0.86 KDM4E (0.52) EPHX1KMT2ATDP1LMNAL3MBTL1
SCHEMBL12172537 0.86 EPHX1 (0.47) EPHX1KMT2ATDP1LMNASLC6A2
SCHEMBL13143807 0.85 TDP1 (0.46) EPHX1KMT2ATDP1LMNASLC6A2
SCHEMBL14277073 0.84 EPHX1 (0.56) EPHX1KMT2ATDP1L3MBTL1MEN1
SCHEMBL29853739 0.82 TDP1 (0.66) KMT2ATDP1LMNASLC6A2SLC6A3
SCHEMBL4645175 0.82 TDP1 (0.66) KMT2ATDP1LMNASLC6A2SLC6A3
SCHEMBL31326117 0.81 EPHX1 (0.54) EPHX1KMT2AL3MBTL1NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576359-A ANTHRACENE DERIVATIVE, SOLVENT, COMPOUND CONTAINING GLYCIDYL GROUPS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-19 US disclosed
EP-0636941-B1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEM IND LTD (JP) 1996-03-20 EP disclosed
EP-0636941-A1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-02-01 EP disclosed