SCHEMBL8943867

SCHEMBL8943867

Oc1cc(-c2cccc3ccccc23)nc(S)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 4/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MCL1 Q07820 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
KDM6B O15054 1/20 0.40
FTO Q9C0B1 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5750835 0.80 MEN1 (0.48) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL13133540 0.74 MEN1 (0.54) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL3451007 0.73 MEN1 (0.48) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL10498384 0.73 CYP1A2 (0.45) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL17970015 0.72 MEN1 (0.53) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL17969988 0.72 MEN1 (0.53) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL28245947 0.71 MEN1 (0.65) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL14198210 0.69 ALDH1A1 (0.51) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL23273210 0.69 MEN1 (0.50) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL16805033 0.69 MEN1 (0.50) MEN1KMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480716-A MULTILAYER ELEMENT WITH SUPPORT AND MAGNETIC LAYER WITH FERROMAGNETIC METALS FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed