SCHEMBL8943881

SCHEMBL8943881

CCCCc1cc(O)nc(S)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.43
GPR84 Q9NQS5 6/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
IKBKB O14920 1/20 0.37
KCNH2 Q12809 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.35
DRD2 P14416 1/20 0.35
HTR6 P50406 1/20 0.35
HRH2 P25021 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
SREBF2 Q12772 1/20 0.35
TYR P14679 1/20 0.34
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944425 0.95 GPR84 (0.45) NOS2GPR84ESR1KCNH2KDM4E
SCHEMBL8944169 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944342 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944125 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944114 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944195 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944038 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL8944207 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL6927982 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT
SCHEMBL6931323 0.93 GPR84 (0.46) NOS2GPR84ESR1KCNH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480716-A MULTILAYER ELEMENT WITH SUPPORT AND MAGNETIC LAYER WITH FERROMAGNETIC METALS FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed