SCHEMBL8943940

SCHEMBL8943940

COc1ccc(N(c2ccccc2)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.72
PGR P06401 4/20 0.57
CA4 P22748 1/20 0.56
ALDH1A1 P00352 2/20 0.50
HTT P42858 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
NR3C1 P04150 1/20 0.50
TSHR P16473 1/20 0.48
RNF4 P78317 1/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943612 0.98 LTA4H (0.68) LTA4HPGRCA4ALDH1A1HTT
SCHEMBL8943843 0.98 LTA4H (0.75) LTA4HPGRCA4ALDH1A1HTT
SCHEMBL8944066 0.98 LTA4H (0.75) LTA4HPGRCA4ALDH1A1HTT
SCHEMBL23866712 0.92 LTA4H (0.67) LTA4HPGRCA4ALDH1A1HTT
SCHEMBL13720899 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT
SCHEMBL10065630 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT
SCHEMBL578164 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT
SCHEMBL13720596 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT
SCHEMBL13720711 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT
SCHEMBL3339294 0.92 CA4 (0.59) LTA4HPGRCA4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed