Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943493 | 0.99 | FPR2 (0.34) | FPR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8944098 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8943876 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8943949 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8943537 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8944200 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8944391 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8944113 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8943530 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD | |
| SCHEMBL8943836 | 0.98 | FPR2 (0.35) | FPR2ALOX5EPHX1RARBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |