Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 18/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547978 | 0.92 | LTB4R2 (0.54) | LTB4R2AGTR1 | |
| SCHEMBL8944295 | 0.87 | AGTR1 (0.38) | LTB4R2AGTR1 | |
| SCHEMBL8550196 | 0.85 | LTB4R2 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL8550853 | 0.79 | LTB4R2 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL8547981 | 0.79 | AGTR1 (0.42) | LTB4R2AGTR1 | |
| SCHEMBL8553533 | 0.77 | LTB4R2 (0.45) | LTB4R2AGTR1 | |
| SCHEMBL8552360 | 0.74 | LTB4R2 (0.58) | LTB4R2AGTR1 | |
| SCHEMBL8944237 | 0.73 | LTB4R2 (0.62) | LTB4R2AGTR1 | |
| SCHEMBL8549173 | 0.71 | LTB4R2 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL8550200 | 0.71 | AGTR1 (0.47) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500427-A | ANGIOTENSIN II ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-19 | — | — | US | disclosed |