Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827480 | 0.86 | MAPT (0.52) | NPC1RECQLRAB9APRSS1ALDH1A1 | |
| SCHEMBL25725903 | 0.84 | AKR1C3 (0.55) | NPC1RECQLRAB9APRSS1ALDH1A1 | |
| SCHEMBL16770471 | 0.84 | NPC1 (0.73) | NPC1RECQLRAB9ATDP1ALDH1A1 | |
| SCHEMBL5098363 | 0.83 | S1PR4 (0.50) | NPC1RECQLRAB9ATSHRTDP1 | |
| SCHEMBL16861180 | 0.83 | TDP1 (0.50) | NPC1RECQLRAB9ATSHRTDP1 | |
| SCHEMBL10542203 | 0.82 | MAPT (0.57) | NPC1RECQLRAB9AALDH1A1KMT2A | |
| SCHEMBL10884859 | 0.81 | TSHR (0.48) | NPC1RECQLRAB9ATSHRTDP1 | |
| SCHEMBL28776670 | 0.81 | ALDH1A1 (0.52) | NPC1RECQLRAB9ATDP1PRSS1 | |
| SCHEMBL4653935 | 0.80 | ALDH1A1 (0.49) | TDP1PRSS1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28587136 | 0.80 | KDM4E (0.55) | NPC1RECQLRAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5503640-A | ALKYLTHIO PARA-AMINOPHENOLS IN AQUEOUS VEHICLE FOR DYEING HUMAN HAIR | L'OREAL (FR) | 1996-04-02 | — | — | US | disclosed |
| US-5364413-A | Oxidation color dyes for hair | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |