Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8393009 | 0.90 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL9040858 | 0.88 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9095466 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL9097607 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| Trifluoroacetic Acid SCHEMBL9041957 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL9043603 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL8944873 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL8944551 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2 | |
| Water SCHEMBL9096313 | 0.79 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8944678 | 0.78 | AGTR1 (0.58) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |