SCHEMBL8944699

SCHEMBL8944699

CC/C=C\Oc1ccc(-c2ccc(-c3ccc(C4CCC(C)OC4)cc3F)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.33
FPR2 P25090 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944904 0.93 FASN (0.32) FASNFPR2
SCHEMBL12999792 0.89 FPR2 (0.33) FASNFPR2
SCHEMBL8944944 0.89 FASN (0.30) FASNFPR2
SCHEMBL8945046 0.89 FPR2 (0.33) FASNFPR2
SCHEMBL8948065 0.87 FPR2 (0.33) FPR2
SCHEMBL15726830 0.87 FASN (0.42) FASNFPR2
SCHEMBL8946726 0.87 FPR2 (0.31) FPR2
SCHEMBL13000209 0.85 FPR2 (0.33) FASNFPR2
SCHEMBL13000172 0.85 FPR2 (0.38) FPR2
SCHEMBL8944822 0.84 FPR2 (0.32) FASNFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed