SCHEMBL8944709

SCHEMBL8944709

COC(=O)C(=O)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
PKM P14618 1/20 0.49
RECQL P46063 2/20 0.49
POLB P06746 3/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 1/20 0.46
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.44
EZH2 Q15910 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3295977 0.86 RECQL (0.57) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL8944648 0.83 MEN1 (0.53) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL9154782 0.81 GAA (0.52) ATML3MBTL1KMT2ARECQLPOLB
SCHEMBL9154314 0.81 GAA (0.52) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL3422383 0.79 RECQL (0.50) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL19551259 0.78 ATM (0.45) ATML3MBTL1MEN1KMT2APKM
SCHEMBL10525290 0.78 RECQL (0.57) ATML3MBTL1MEN1KMT2APKM
SCHEMBL2956173 0.78 GAA (0.50) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL31142149 0.78 RECQL (0.49) ATML3MBTL1MEN1KMT2ARECQL
SCHEMBL109129 0.78 RECQL (0.49) ATML3MBTL1MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1410921-B1 Ink jet recording material and light-stabilising compound AGFA GEVAERT (BE) 2007-09-05 EP disclosed
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
US-5101033-A Piperidinyl-N-aminooxamides ATOCHEM NORTH AMERICA, INC. (US) 1992-03-31 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
EP-0410970-A4 REACTIVE HINDERED AMINE LIGHT STABILIZERS 1991-07-31 EP disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
EP-0410970-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS. ATOCHEM NORTH AMERICA (US) 1991-02-06 EP disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed