SCHEMBL8944648

SCHEMBL8944648

CCOC(=O)C(=O)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
POLB P06746 2/20 0.48
RECQL P46063 2/20 0.48
MAPT P10636 1/20 0.48
GAA P10253 2/20 0.46
HTT P42858 2/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GLA P06280 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10991852 0.83 KMT2A (0.52) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL8944709 0.83 ATM (0.50) MEN1KMT2AALDH1A1POLBRECQL
SCHEMBL9154360 0.82 MEN1 (0.49) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL3295977 0.80 RECQL (0.57) MEN1KMT2AALDH1A1POLBRECQL
SCHEMBL11529923 0.77 ALDH1A1 (0.44) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL8944757 0.77 GAA (0.56) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL15294792 0.77 EGLN1 (0.47) ALDH1A1MAPTGAAHTTHSD17B10
SCHEMBL8029546 0.76 MEN1 (0.46) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL9154782 0.75 GAA (0.52) KMT2AALDH1A1POLBRECQLGAA
SCHEMBL9154314 0.75 GAA (0.52) MEN1KMT2AALDH1A1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578731-A ASYMMETRICAL HYDRAZINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1996-11-26 US disclosed
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
US-5554754-A PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
US-5470980-A Light stabilizers for polymers that can be grafted to polymers CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0647626-A1 Azadicarboxylic acid derivatives containing hindered amine moieties as polymer stabilisers CIBA-GEIGY AG (CH) 1995-04-12 EP disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5318851-A Curable composition with auxiliary curing agent; coatings ELF ATOCHEM N.A., INC. (US) 1994-06-07 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
EP-0410970-A4 REACTIVE HINDERED AMINE LIGHT STABILIZERS 1991-07-31 EP disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
EP-0410970-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS. ATOCHEM NORTH AMERICA (US) 1991-02-06 EP disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed