Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944397 | 1.00 | EPHX2 (0.53) | EPHX2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL8944752 | 0.99 | EPHX2 (0.51) | EPHX2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL8392576 | 0.96 | GRIN2B (0.48) | EPHX2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL8396273 | 0.93 | GRIN2B (0.50) | EPHX2NPC1RAB9AALDH1A1GRIN2B | |
| SCHEMBL8392063 | 0.92 | NPC1 (0.55) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8395708 | 0.92 | NPC1 (0.55) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8396686 | 0.90 | SMN1; SMN2 (0.56) | EPHX2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL9293477 | 0.89 | GRIN2B (0.43) | EPHX2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL8394496 | 0.88 | SMN1; SMN2 (0.56) | EPHX2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8395679 | 0.86 | EPHX2 (0.54) | EPHX2EPHX1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |