Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944752 | 0.94 | EPHX2 (0.51) | GRIN2BMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8392576 | 0.94 | GRIN2B (0.48) | GRIN2BMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8944739 | 0.93 | EPHX2 (0.53) | GRIN2BSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8944397 | 0.93 | EPHX2 (0.53) | GRIN2BSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8944652 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ARECQLLMNA | |
| SCHEMBL27493272 | 0.90 | NAAA (0.55) | SMN1; SMN2NPC1RAB9ARECQLLMNA | |
| SCHEMBL9293477 | 0.87 | GRIN2B (0.43) | GRIN2BMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8394496 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ARECQLLMNA | |
| SCHEMBL8396686 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ARECQLLMNA | |
| SCHEMBL8944423 | 0.85 | HRH4 (0.51) | MGLLSMN1; SMN2NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |