Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751181 | 0.88 | MAPT (0.49) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL8021643 | 0.85 | POLB (0.41) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7039125 | 0.85 | MEN1 (0.43) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL19146292 | 0.85 | PDE3B (0.54) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL8034924 | 0.85 | PDE3B (0.42) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7038887 | 0.85 | MEN1 (0.43) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL23885601 | 0.80 | KDM4E (0.49) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7983948 | 0.80 | KDM4E (0.61) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL31195781 | 0.80 | KDM4E (0.61) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL31335845 | 0.78 | MAPT (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | claimed |
| EP-0496653-B1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | OREAL (FR) | 1995-09-13 | — | — | EP | claimed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | claimed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | claimed |
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | disclosed |
| US-5518505-A | Compositions and methods for the dyeing of keratinous fibers with oxidation dye precursors, indole derivative couplers and oxidizing agents | L'OREAL (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0496653-B1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | OREAL (FR) | 1995-09-13 | — | — | EP | disclosed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | disclosed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | disclosed |